Structure of S6 kinase 1 determines whether raptor-mTOR or rictor-mTOR phosphorylates its hydrophobic motif site. [electronic resource]
Producer: 20050708Description: 19445-8 p. digitalISSN:- 0021-9258
- Amino Acid Motifs
- Animals
- Catalytic Domain -- genetics
- Cell Line
- Humans
- Hydrophobic and Hydrophilic Interactions
- In Vitro Techniques
- Models, Biological
- Mutagenesis, Site-Directed
- Phosphorylation
- Protein Kinases -- genetics
- Protein Structure, Tertiary
- RNA Interference
- Rats
- Recombinant Proteins -- chemistry
- Ribosomal Protein S6 Kinases -- chemistry
- TOR Serine-Threonine Kinases
- Threonine -- chemistry
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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