Sensitivity of undifferentiated, high-TCR density CD8+ cells to methylene groups appended to tumor antigen determines their differentiation or death. [electronic resource]
Producer: 20050526Description: 2930-7 p. digitalISSN:- 0008-5472
- Antigens, Neoplasm -- chemistry
- Apoptosis -- immunology
- CD8-Positive T-Lymphocytes -- cytology
- Caspase 9
- Caspase Inhibitors
- Caspases -- metabolism
- Cell Differentiation -- immunology
- Enzyme Activation
- Epitopes, T-Lymphocyte -- chemistry
- Female
- Humans
- Interferon-gamma -- immunology
- Lymphocyte Activation -- immunology
- Membrane Glycoproteins -- biosynthesis
- Models, Molecular
- Oligopeptides -- immunology
- Ovarian Neoplasms -- immunology
- Perforin
- Pore Forming Cytotoxic Proteins
- Receptor, ErbB-2 -- immunology
- Receptors, Antigen, T-Cell -- immunology
- Structure-Activity Relationship
- T-Lymphocytes, Cytotoxic -- immunology
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Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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