Prolidase, a potential enzyme target for melanoma: design of proline-containing dipeptide-like prodrugs. [electronic resource]
Producer: 20050512Description: 37-46 p. digitalISSN:- 1543-8384
- Amino Acid Sequence
- Antineoplastic Agents
- Caco-2 Cells
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Colorimetry
- Dipeptidases -- therapeutic use
- Drug Design
- Feasibility Studies
- Humans
- K562 Cells
- Melanoma -- drug therapy
- Melphalan -- analogs & derivatives
- Oligonucleotide Array Sequence Analysis
- Prodrugs -- chemical synthesis
- Proline -- analogs & derivatives
- Reverse Transcriptase Polymerase Chain Reaction
- Substrate Specificity
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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