Ribozyme cleavage leads to decreased expression of fibroblast growth factor receptor 3 in human multiple myeloma cells, which is associated with apoptosis and downregulation of vascular endothelial growth factor. [electronic resource]
Producer: 20050711Description: 1-11 p. digitalISSN:- 1545-4576
- Apoptosis
- Blotting, Western
- Catalysis
- Cell Cycle
- Cell Line
- Cell Line, Tumor
- Cell Proliferation
- Cell Survival
- Cell-Free System
- Chromosomes, Human, Pair 14
- Chromosomes, Human, Pair 4
- DNA -- metabolism
- Down-Regulation
- Humans
- Immunohistochemistry
- Models, Genetic
- Multiple Myeloma -- metabolism
- Plasmids -- metabolism
- Polymerase Chain Reaction
- Protein-Tyrosine Kinases -- biosynthesis
- RNA, Catalytic -- chemistry
- RNA, Messenger -- metabolism
- Receptor, Fibroblast Growth Factor, Type 3
- Receptors, Fibroblast Growth Factor -- biosynthesis
- Reverse Transcriptase Polymerase Chain Reaction
- Thymidine -- chemistry
- Transfection
- Translocation, Genetic
- Tumor Cells, Cultured
- Up-Regulation
- Vascular Endothelial Growth Factor A -- biosynthesis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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