Key roles of BIM-driven apoptosis in epithelial tumors and rational chemotherapy. [electronic resource]
Producer: 20050503Description: 227-38 p. digitalISSN:- 1535-6108
- Animals
- Antineoplastic Agents, Phytogenic -- metabolism
- Apoptosis -- physiology
- Apoptosis Regulatory Proteins
- Bcl-2-Like Protein 11
- Boronic Acids -- therapeutic use
- Bortezomib
- Carrier Proteins -- genetics
- Cell Line
- Drug Resistance, Neoplasm
- Drug Therapy, Combination
- Gene Expression Regulation
- Genes, ras
- Humans
- MAP Kinase Signaling System -- physiology
- Membrane Proteins -- genetics
- Mice
- Mice, Knockout
- Neoplasms, Glandular and Epithelial -- drug therapy
- Paclitaxel -- metabolism
- Protease Inhibitors -- therapeutic use
- Proteasome Endopeptidase Complex -- metabolism
- Proteasome Inhibitors
- Proto-Oncogene Proteins -- genetics
- Pyrazines -- therapeutic use
- Tumor Suppressor Protein p53 -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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