Inhibition of neutrophil apoptosis by TLR agonists in whole blood: involvement of the phosphoinositide 3-kinase/Akt and NF-kappaB signaling pathways, leading to increased levels of Mcl-1, A1, and phosphorylated Bad. [electronic resource]
Producer: 20050428Description: 3633-42 p. digitalISSN:- 0022-1767
- Apoptosis -- drug effects
- Carrier Proteins -- metabolism
- Caspase 3
- Caspases -- metabolism
- DNA-Binding Proteins -- metabolism
- Humans
- In Vitro Techniques
- Membrane Glycoproteins -- agonists
- Mitochondria -- drug effects
- Myeloid Cell Leukemia Sequence 1 Protein
- NF-kappa B -- metabolism
- Neoplasm Proteins -- metabolism
- Neutrophils -- cytology
- Phosphatidylinositol 3-Kinases -- metabolism
- Phosphorylation
- Protein Serine-Threonine Kinases -- metabolism
- Proto-Oncogene Proteins -- metabolism
- Proto-Oncogene Proteins c-akt
- Proto-Oncogene Proteins c-bcl-2 -- metabolism
- Receptors, Cell Surface -- agonists
- Replication Protein C
- Signal Transduction
- Toll-Like Receptor 1
- Toll-Like Receptor 2
- Toll-Like Receptor 4
- Toll-Like Receptor 5
- Toll-Like Receptor 7
- Toll-Like Receptor 9
- Toll-Like Receptors
- bcl-Associated Death Protein
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Publication Type: Journal Article
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