Joint and bone disease in mucopolysaccharidoses VI and VII: identification of new therapeutic targets and biomarkers using animal models. [electronic resource]
Producer: 20050728Description: 701-7 p. digitalISSN:- 0031-3998
- Animals
- Antimetabolites -- pharmacology
- Apoptosis
- Biomarkers -- metabolism
- Bone Diseases -- complications
- Bromodeoxyuridine -- pharmacology
- Cats
- Cell Proliferation
- Cells, Cultured
- Chondrocytes -- cytology
- Cytokines -- metabolism
- Disease Models, Animal
- Dogs
- Immunoassay
- Immunohistochemistry
- Inflammation
- Joint Diseases -- complications
- Matrix Metalloproteinase 2 -- biosynthesis
- Matrix Metalloproteinase 9 -- biosynthesis
- Mucopolysaccharidosis VI -- complications
- Mucopolysaccharidosis VII -- complications
- Nitric Oxide -- metabolism
- Osteonectin -- metabolism
- Rats
- Reverse Transcriptase Polymerase Chain Reaction
- Tibia -- metabolism
- Time Factors
- Tissue Inhibitor of Metalloproteinase-1 -- biosynthesis
- Transforming Growth Factor beta -- biosynthesis
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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