Angiogenesis inhibition by vascular endothelial growth factor receptor-2 blockade reduces stromal matrix metalloproteinase expression, normalizes stromal tissue, and reverts epithelial tumor phenotype in surface heterotransplants. [electronic resource]
Producer: 20050404Description: 1294-305 p. digitalISSN:- 0008-5472
- Animals
- Antibodies, Monoclonal -- pharmacology
- Carcinoma, Squamous Cell -- blood supply
- Cell Growth Processes -- physiology
- Cell Line, Tumor
- Collagenases -- biosynthesis
- Humans
- Matrix Metalloproteinase 13
- Matrix Metalloproteinase 9 -- biosynthesis
- Matrix Metalloproteinase Inhibitors
- Mice
- Mice, Nude
- Neoplasm Transplantation
- Neovascularization, Pathologic -- enzymology
- Phenotype
- Stromal Cells -- enzymology
- Transplantation, Heterologous
- Vascular Endothelial Growth Factor Receptor-2 -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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