Peutz-Jeghers LKB1 mutants fail to activate GSK-3beta, preventing it from inhibiting Wnt signaling. [electronic resource]
Producer: 20050711Description: 184-96 p. digitalISSN:- 1617-4615
- AMP-Activated Protein Kinase Kinases
- Cytoskeletal Proteins -- metabolism
- Flow Cytometry
- Gene Expression Regulation
- Genetic Vectors
- Glycogen Synthase Kinase 3 -- metabolism
- Glycogen Synthase Kinase 3 beta
- HeLa Cells
- Humans
- Immunoblotting
- Intercellular Signaling Peptides and Proteins -- metabolism
- Lentivirus
- Luciferases -- metabolism
- Mutation -- genetics
- Oligonucleotide Array Sequence Analysis
- Peutz-Jeghers Syndrome -- genetics
- Phosphorylation
- Protein Serine-Threonine Kinases -- genetics
- Reverse Transcriptase Polymerase Chain Reaction
- Signal Transduction -- physiology
- Trans-Activators -- metabolism
- Transfection
- Wnt Proteins
- beta Catenin
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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