The CXCR4 agonist peptide, CTCE-0021, rapidly mobilizes polymorphonuclear neutrophils and hematopoietic progenitor cells into peripheral blood and synergizes with granulocyte colony-stimulating factor. [electronic resource]
Producer: 20050511Description: 295-307 p. digitalISSN:- 0301-472X
- Animals
- Chemokine CXCL12
- Chemokines, CXC -- administration & dosage
- Dose-Response Relationship, Drug
- Down-Regulation -- drug effects
- Drug Synergism
- Female
- Granulocyte Colony-Stimulating Factor -- administration & dosage
- Hematopoietic Stem Cell Mobilization
- Hematopoietic Stem Cells -- physiology
- Injections, Subcutaneous
- Mice
- Mice, Inbred BALB C
- Neutrophils -- physiology
- Peptides -- administration & dosage
- Receptors, CXCR4 -- agonists
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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