Macrophages induce the inflammatory response in the pulmonary Arthus reaction through G alpha i2 activation that controls C5aR and Fc receptor cooperation. [electronic resource]
Producer: 20050419Description: 3041-50 p. digitalISSN:- 0022-1767
- Animals
- Arthus Reaction -- immunology
- Cell Line
- Complement C5a -- physiology
- GTP-Binding Protein alpha Subunit, Gi2
- GTP-Binding Protein alpha Subunits, Gi-Go -- metabolism
- Hot Temperature
- Immunoglobulin G -- pharmacology
- Inflammation Mediators -- metabolism
- Lung -- immunology
- Macrophage Activation -- immunology
- Macrophages, Alveolar -- immunology
- Membrane Proteins -- biosynthesis
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Proto-Oncogene Proteins -- metabolism
- Receptor Cross-Talk -- immunology
- Receptor, Anaphylatoxin C5a
- Receptors, Complement -- biosynthesis
- Receptors, Fc -- metabolism
- Receptors, IgG -- deficiency
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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