Gefitinib (Iressa, ZD1839) inhibits SN38-triggered EGF signals and IL-8 production in gastric cancer cells. [electronic resource]
Producer: 20050621Description: 584-94 p. digitalISSN:- 0344-5704
- Amphiregulin
- Antineoplastic Agents -- pharmacology
- Camptothecin -- analogs & derivatives
- Cell Line, Tumor
- Drug Screening Assays, Antitumor
- EGF Family of Proteins
- Epidermal Growth Factor -- metabolism
- ErbB Receptors -- metabolism
- Gefitinib
- Glycoproteins -- metabolism
- Heparin-binding EGF-like Growth Factor
- Humans
- Intercellular Signaling Peptides and Proteins -- metabolism
- Interleukin-8 -- metabolism
- Irinotecan
- Phosphorylation
- Quinazolines -- pharmacology
- Reactive Oxygen Species -- metabolism
- Signal Transduction -- drug effects
- Stomach Neoplasms -- pathology
- Transforming Growth Factor alpha -- metabolism
- Tyrosine -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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