Application of a flexible synthesis of (5R)-thiolactomycin to develop new inhibitors of type I fatty acid synthase. [electronic resource]
Producer: 20050405Description: 946-61 p. digitalISSN:- 0022-2623
- Animals
- Anti-Obesity Agents -- chemical synthesis
- Antineoplastic Agents -- chemical synthesis
- Body Weight -- drug effects
- Cell Line, Tumor
- Drug Screening Assays, Antitumor
- Fatty Acid Synthases -- antagonists & inhibitors
- Humans
- Mice
- Mice, Inbred BALB C
- Models, Molecular
- Stereoisomerism
- Structure-Activity Relationship
- Thiophenes -- chemical synthesis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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