Tumor necrosis factor induces the loss of sphingosine kinase-1 by a cathepsin B-dependent mechanism. [electronic resource]
Producer: 20050621Description: 17196-202 p. digitalISSN:- 0021-9258
- Apoptosis
- Caspase 7
- Caspase 8
- Caspase Inhibitors
- Caspases -- metabolism
- Cathepsin B -- metabolism
- Cell Death
- Cell Line, Tumor
- Cysteine Endopeptidases -- metabolism
- Cytosol -- metabolism
- Dose-Response Relationship, Drug
- Down-Regulation
- Electrophoresis, Polyacrylamide Gel
- Enzyme Activation
- Enzyme Inhibitors -- pharmacology
- Humans
- Immunoblotting
- Lysosomes -- chemistry
- Mass Spectrometry
- Microscopy, Fluorescence
- Phosphotransferases (Alcohol Group Acceptor) -- metabolism
- Protein Binding
- RNA, Small Interfering -- metabolism
- Recombinant Proteins -- chemistry
- Time Factors
- Transfection
- Tumor Necrosis Factor-alpha -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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