Endostatin's heparan sulfate-binding site is essential for inhibition of angiogenesis and enhances in situ binding to capillary-like structures in bone explants. [electronic resource]
Producer: 20050628Description: 557-61 p. digitalISSN:- 0945-053X
- Animals
- Binding Sites
- Bone Development
- Bone and Bones -- blood supply
- Capillaries -- metabolism
- Cells, Cultured
- Collagen Type XVIII -- biosynthesis
- Dose-Response Relationship, Drug
- Endostatins -- biosynthesis
- Endothelial Cells -- cytology
- Heparitin Sulfate -- chemistry
- Humans
- Mice
- Mutation
- Neovascularization, Pathologic
- Protein Binding
- Recombinant Proteins -- chemistry
- Sodium Chloride -- pharmacology
- Time Factors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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