Compacted DNA nanoparticles administered to the nasal mucosa of cystic fibrosis subjects are safe and demonstrate partial to complete cystic fibrosis transmembrane regulator reconstitution. [electronic resource]
Producer: 20050421Description: 1255-69 p. digitalISSN:- 1043-0342
- Administration, Intranasal
- C-Reactive Protein -- analysis
- Clinical Protocols
- Complement System Proteins -- analysis
- Cystic Fibrosis -- drug therapy
- Cystic Fibrosis Transmembrane Conductance Regulator -- administration & dosage
- DNA -- genetics
- Double-Blind Method
- Gene Transfer Techniques
- Genetic Therapy -- methods
- Genetic Vectors
- Interleukin-6 -- blood
- Nanostructures -- chemistry
- Nasal Lavage Fluid
- Nasal Mucosa -- metabolism
- Polymerase Chain Reaction
- Time Factors
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Publication Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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