Hematopoietic cytokines enhance Chk1-dependent G2/M checkpoint activation by etoposide through the Akt/GSK3 pathway to inhibit apoptosis. [electronic resource]
Producer: 20050418Description: 1973-81 p. digitalISSN:- 0950-9232
- Animals
- Apoptosis -- drug effects
- Cell Cycle -- drug effects
- Cell Division -- drug effects
- Cell Line
- Cell Line, Tumor
- Checkpoint Kinase 1
- Cytokines -- pharmacology
- Erythropoietin -- pharmacology
- Etoposide -- pharmacology
- Flow Cytometry
- G2 Phase -- drug effects
- Glycogen Synthase Kinase 3 -- drug effects
- Humans
- Interleukin-3 -- pharmacology
- Leukemia
- Mice
- Phosphorylation
- Phosphotyrosine -- metabolism
- Protein Kinases -- metabolism
- Protein Serine-Threonine Kinases -- drug effects
- Proto-Oncogene Proteins -- drug effects
- Proto-Oncogene Proteins c-akt
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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