PAR-4 is involved in regulation of beta-secretase cleavage of the Alzheimer amyloid precursor protein. [electronic resource]
Producer: 20050621Description: 13824-32 p. digitalISSN:- 0021-9258
- Alzheimer Disease -- metabolism
- Amyloid Precursor Protein Secretases
- Amyloid beta-Peptides -- metabolism
- Amyloid beta-Protein Precursor -- genetics
- Animals
- Apoptosis Regulatory Proteins
- Aspartic Acid Endopeptidases
- Cells, Cultured
- Endopeptidases -- genetics
- Humans
- Intracellular Signaling Peptides and Proteins -- genetics
- Mice
- Neurons -- cytology
- Protein Structure, Tertiary
- RNA Interference
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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