Tumor necrosis factor alpha and phorbol 12-myristate-13-acetate down-regulate human 11beta-hydroxysteroid dehydrogenase type 2 through p50/p50 NF-kappaB homodimers and Egr-1. [electronic resource]
Producer: 20051214Description: 650-2 p. digitalISSN:- 1530-6860
- 11-beta-Hydroxysteroid Dehydrogenase Type 2 -- genetics
- Animals
- Cell Line
- Colon
- DNA -- metabolism
- DNA Footprinting
- Dimerization
- Early Growth Response Protein 1 -- metabolism
- Gene Expression Regulation, Enzymologic -- drug effects
- Humans
- Kidney -- enzymology
- Mice
- Mice, Transgenic
- NF-kappa B p50 Subunit -- metabolism
- Promoter Regions, Genetic -- genetics
- RNA, Messenger -- analysis
- Tetradecanoylphorbol Acetate -- pharmacology
- Tumor Necrosis Factor-alpha -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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