Alternative mRNA splicing of SMRT creates functional diversity by generating corepressor isoforms with different affinities for different nuclear receptors. [electronic resource]
Producer: 20050407Description: 7493-503 p. digitalISSN:- 0021-9258
- Alternative Splicing
- Animals
- Blotting, Western
- Cell Line
- Cell Line, Tumor
- DNA -- chemistry
- DNA, Complementary -- metabolism
- DNA-Binding Proteins -- biosynthesis
- Databases as Topic
- Dimerization
- Dose-Response Relationship, Drug
- Expressed Sequence Tags
- Genes, Dominant
- Humans
- Mice
- Mice, Inbred C57BL
- Muramidase -- chemistry
- Nuclear Receptor Co-Repressor 2
- Open Reading Frames
- Plasmids -- metabolism
- Protein Binding
- Protein Isoforms
- Protein Structure, Tertiary
- RNA, Messenger -- metabolism
- Repressor Proteins -- biosynthesis
- Reverse Transcriptase Polymerase Chain Reaction
- Sequence Analysis, DNA
- Software
- Tissue Distribution
- Transcription, Genetic
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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