Effects of systemic endothelin A receptor antagonism in various vascular beds in men: in vivo interactions of the major blood pressure-regulating systems and associations with the GNB3 C825T polymorphism. [electronic resource]
Producer: 20041202Description: 396-408 p. digitalISSN:- 0009-9236
- Adult
- Angiotensin II -- blood
- Blood Pressure -- drug effects
- Cross-Over Studies
- Double-Blind Method
- Endothelin A Receptor Antagonists
- Endothelins -- genetics
- Female
- Genotype
- Hand -- blood supply
- Hemodynamics -- drug effects
- Heterotrimeric GTP-Binding Proteins -- genetics
- Humans
- Male
- Microcirculation -- drug effects
- Neurotransmitter Agents -- metabolism
- Phenylpropionates -- pharmacokinetics
- Polymorphism, Genetic -- genetics
- Pyrimidines -- pharmacokinetics
- Regional Blood Flow -- drug effects
- Renin-Angiotensin System -- genetics
- Skin -- blood supply
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Publication Type: Clinical Trial; Journal Article; Randomized Controlled Trial
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