Altered processing of the amyloid precursor protein and decreased expression of ADAM 10 by chronic hypoxia in SH-SY5Y: no role for the stress-activated JNK and p38 signalling pathways. [electronic resource]
Producer: 20050330Description: 161-9 p. digitalISSN:- 0169-328X
- ADAM Proteins
- ADAM10 Protein
- Amyloid Precursor Protein Secretases
- Amyloid beta-Protein Precursor -- metabolism
- Anthracenes -- pharmacology
- Blotting, Western -- methods
- Cell Hypoxia -- physiology
- Cell Line, Tumor
- Enzyme Inhibitors -- pharmacology
- Gene Expression Regulation -- drug effects
- Humans
- JNK Mitogen-Activated Protein Kinases -- metabolism
- MAP Kinase Kinase 4
- Membrane Proteins -- genetics
- Metalloendopeptidases -- genetics
- Mitogen-Activated Protein Kinase Kinases -- metabolism
- Neuroblastoma -- drug therapy
- Oxazoles -- pharmacology
- Pyridines -- pharmacology
- Signal Transduction -- drug effects
- Stress, Physiological -- metabolism
- Time Factors
- p38 Mitogen-Activated Protein Kinases -- metabolism
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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