Mutations of Pneumocystis jirovecii dihydrofolate reductase associated with failure of prophylaxis. [electronic resource]
Producer: 20041221Description: 4301-5 p. digitalISSN:- 0066-4804
- Adult
- Amino Acid Sequence
- Anti-Bacterial Agents -- pharmacology
- Bronchoalveolar Lavage Fluid -- microbiology
- Cloning, Molecular
- DNA, Fungal -- biosynthesis
- Drug Resistance, Fungal -- genetics
- Evolution, Molecular
- Female
- Folic Acid Antagonists -- pharmacology
- HIV Infections -- complications
- Humans
- Male
- Middle Aged
- Molecular Sequence Data
- Mutation -- genetics
- Plasmids -- genetics
- Pneumocystis -- genetics
- Pneumocystis Infections -- prevention & control
- Pyrimethamine -- pharmacology
- Reverse Transcriptase Polymerase Chain Reaction
- Tetrahydrofolate Dehydrogenase -- genetics
- Trimethoprim, Sulfamethoxazole Drug Combination -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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