In human immature BFU-E tumor necrosis factor-alpha not only downregulates CDK6 but also directly produces apoptosis which is prevented by stem cell factor. [electronic resource]
Producer: 20041216Description: 911-7 p. digitalISSN:- 0301-472X
- Apoptosis -- drug effects
- CASP8 and FADD-Like Apoptosis Regulating Protein
- Caspases -- metabolism
- Cell Count
- Cell Proliferation -- drug effects
- Cells, Cultured
- Cyclin-Dependent Kinase 6
- Cyclin-Dependent Kinases -- drug effects
- Down-Regulation -- drug effects
- Erythroid Precursor Cells -- cytology
- Humans
- Intracellular Signaling Peptides and Proteins -- analysis
- Stem Cell Factor -- pharmacology
- Tumor Necrosis Factor-alpha -- pharmacology
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Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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