Gene therapy for sarcoma utilizing adenoviral transfer of the beta-glucuronidase and bax genes and an anthracyline prodrug. [electronic resource]
Producer: 20041123Description: 153-8 p. digitalISSN:- 0022-4804
- Adenoviridae -- genetics
- Animals
- Anthracyclines -- therapeutic use
- Antibiotics, Antineoplastic -- therapeutic use
- Apoptosis -- genetics
- Cell Line, Tumor
- Combined Modality Therapy
- Doxorubicin -- analogs & derivatives
- Drug Screening Assays, Antitumor
- Fibrosarcoma -- metabolism
- Gene Transfer Techniques
- Genetic Therapy
- Genetic Vectors
- Glucuronates -- therapeutic use
- Glucuronidase -- genetics
- Intracellular Membranes -- metabolism
- Prodrugs -- therapeutic use
- Proto-Oncogene Proteins c-bcl-2 -- genetics
- Rats
- Rats, Inbred F344
- bcl-2-Associated X Protein
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Publication Type: Evaluation Study; Journal Article
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