Rare, highly pyrimethamine-resistant alleles of the Plasmodium falciparum dihydrofolate reductase gene from 5 African sites. [electronic resource]
Producer: 20041228Description: 1783-92 p. digitalISSN:- 0022-1899
- Alleles
- Amino Acid Substitution
- Animals
- Antimalarials -- pharmacology
- Dapsone -- pharmacology
- Drug Resistance -- genetics
- Gabon
- Genes, Protozoan
- Humans
- Kenya
- Malaria, Falciparum -- drug therapy
- Malawi
- Molecular Epidemiology
- Mutation, Missense
- Nigeria
- Parasitic Sensitivity Tests
- Plasmodium falciparum -- drug effects
- Point Mutation
- Proguanil -- analogs & derivatives
- Pyrimethamine -- pharmacology
- Sulfadoxine -- pharmacology
- Tanzania
- Tetrahydrofolate Dehydrogenase -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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