Macrophage colony stimulatory factor and interferon-gamma trigger distinct mechanisms for augmentation of beta-amyloid-induced microglia-mediated neurotoxicity. [electronic resource]
Producer: 20050324Description: 623-33 p. digitalISSN:- 0022-3042
- Amyloid beta-Peptides -- toxicity
- Animals
- Cells, Cultured
- Coculture Techniques
- Cytokines -- metabolism
- Drug Synergism
- Humans
- Interferon-gamma -- pharmacology
- Macrophage Colony-Stimulating Factor -- pharmacology
- Microglia -- cytology
- Neurons -- cytology
- Nitric Oxide -- metabolism
- Peptide Fragments -- toxicity
- Rats
- Rats, Sprague-Dawley
- Reactive Oxygen Species -- metabolism
- Signal Transduction -- drug effects
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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