Nuclear factor-kappaB and IkappaB kinase are constitutively active in human pancreatic cells, and their down-regulation by curcumin (diferuloylmethane) is associated with the suppression of proliferation and the induction of apoptosis. [electronic resource]
Producer: 20041222Description: 2351-62 p. digitalISSN:- 0008-543X
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Curcumin -- pharmacology
- Down-Regulation
- Electrophoretic Mobility Shift Assay
- Enzyme-Linked Immunosorbent Assay
- Humans
- I-kappa B Kinase
- Immunoblotting
- Interleukin-8 -- metabolism
- NF-kappa B -- drug effects
- Pancreatic Neoplasms -- metabolism
- Protein Serine-Threonine Kinases -- drug effects
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
There are no comments on this title.
Log in to your account to post a comment.