Design and synthesis of aryl diphenolic azoles as potent and selective estrogen receptor-beta ligands. [electronic resource]
Producer: 20041110Description: 5021-40 p. digitalISSN:- 0022-2623
- Androgen Antagonists -- chemical synthesis
- Animals
- Animals, Genetically Modified
- Anti-Inflammatory Agents, Non-Steroidal -- chemical synthesis
- Binding Sites
- Body Temperature -- drug effects
- Bone Diseases, Metabolic -- prevention & control
- Cell Line, Tumor
- Crystallography, X-Ray
- Drug Design
- Estrogen Receptor beta
- Female
- HLA-B27 Antigen -- genetics
- Humans
- Isoxazoles -- chemical synthesis
- Male
- Mice
- Models, Molecular
- Organ Size -- drug effects
- Phenols -- chemical synthesis
- Prostate -- anatomy & histology
- Radioligand Assay
- Rats
- Rats, Sprague-Dawley
- Receptors, Estrogen -- agonists
- Structure-Activity Relationship
- Transcription, Genetic -- drug effects
- Uterus -- anatomy & histology
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Publication Type: Journal Article
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