Antisense strategies for redirection of drug metabolism: using paclitaxel as a model. [electronic resource]
Producer: 20041229Description: 273-92 p. digitalISSN:- 1543-1894
- Animals
- Antineoplastic Agents, Phytogenic -- pharmacokinetics
- Area Under Curve
- Aryl Hydrocarbon Hydroxylases -- metabolism
- Cytochrome P-450 CYP1A1 -- metabolism
- Cytochrome P-450 CYP1A2 -- metabolism
- Cytochrome P-450 CYP3A
- Cytochrome P-450 Enzyme System -- genetics
- Humans
- Liver -- metabolism
- Male
- Membrane Proteins -- metabolism
- Models, Chemical
- Oligonucleotides, Antisense -- therapeutic use
- Paclitaxel -- pharmacokinetics
- Rats
- Rats, Sprague-Dawley
- Time Factors
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Publication Type: Journal Article
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