Role of CYP3A enzymes in the biotransformation of triazolam in rat liver. [electronic resource]
Producer: 20050114Description: 463-71 p. digitalISSN:- 0049-8254
- Adult
- Animals
- Aryl Hydrocarbon Hydroxylases -- antagonists & inhibitors
- Biotransformation
- Cytochrome P-450 CYP3A
- Enzyme Inhibitors -- pharmacology
- GABA-A Receptor Agonists
- Humans
- Hydroxylation
- In Vitro Techniques
- Isoenzymes -- metabolism
- Ketoconazole -- pharmacology
- Kinetics
- Male
- Microsomes, Liver -- drug effects
- Oxidoreductases, N-Demethylating -- antagonists & inhibitors
- Rats
- Rats, Inbred F344
- Recombinant Proteins -- metabolism
- Triazolam -- metabolism
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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