Allosteric modulation and constitutive activity of fusion proteins between the adenosine A1 receptor and different 351Cys-mutated Gi alpha-subunits. [electronic resource]
Producer: 20050216Description: 91-8 p. digitalISSN:- 0014-2999
- Adenosine -- analogs & derivatives
- Allosteric Site -- genetics
- Animals
- Binding, Competitive -- drug effects
- COS Cells
- Cell Membrane -- drug effects
- Cysteine -- genetics
- Dose-Response Relationship, Drug
- GTP-Binding Protein alpha Subunits, Gi-Go -- genetics
- Guanosine 5'-O-(3-Thiotriphosphate) -- metabolism
- Humans
- Mutation
- Radioligand Assay
- Receptor, Adenosine A1 -- genetics
- Recombinant Fusion Proteins -- genetics
- Sodium Chloride -- pharmacology
- Sulfur Radioisotopes
- Thiophenes -- pharmacology
- Transfection
- Tritium
- Xanthines -- metabolism
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Publication Type: Journal Article
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