Cysteinyl-leukotrienes are released from astrocytes and increase astrocyte proliferation and glial fibrillary acidic protein via cys-LT1 receptors and mitogen-activated protein kinase pathway. [electronic resource]
Producer: 20041220Description: 1514-24 p. digitalISSN:- 0953-816X
- Adenosine Triphosphate -- analogs & derivatives
- Animals
- Animals, Newborn
- Astrocytes -- metabolism
- Blotting, Northern -- methods
- Blotting, Western -- methods
- Calcimycin -- pharmacology
- Cell Division -- physiology
- Cell Survival
- Cells, Cultured
- Cerebral Cortex -- cytology
- Cysteine -- classification
- Dose-Response Relationship, Drug
- Drug Interactions
- Enzyme Inhibitors -- pharmacology
- Glial Fibrillary Acidic Protein -- metabolism
- Glucose -- deficiency
- Glutathione Transferase -- genetics
- Hypoxia
- Immunoenzyme Techniques -- methods
- Ionophores -- pharmacology
- Leukotrienes -- classification
- Lipoxygenase -- genetics
- Membrane Proteins -- physiology
- Mitogen-Activated Protein Kinases -- physiology
- RNA, Messenger -- metabolism
- Rats
- Receptors, Leukotriene -- physiology
- Reverse Transcriptase Polymerase Chain Reaction -- methods
- Signal Transduction -- drug effects
- Thionucleotides -- pharmacology
- Thymidine -- metabolism
- Time Factors
- Tritium -- metabolism
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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