Tumor necrosis factor-alpha-converting enzyme (ADAM17) mediates GPIbalpha shedding from platelets in vitro and in vivo. [electronic resource]
Producer: 20050425Description: 677-83 p. digitalISSN:- 1524-4571
- ADAM Proteins
- ADAM17 Protein
- Adenosine Diphosphate -- pharmacology
- Animals
- Blood Platelets -- drug effects
- Carbonyl Cyanide m-Chlorophenyl Hydrazone -- pharmacology
- Dipeptides -- pharmacology
- Hepatocytes -- enzymology
- Humans
- Hydroxamic Acids -- pharmacology
- L-Selectin -- blood
- Male
- Metalloendopeptidases -- deficiency
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Morpholines -- pharmacology
- P-Selectin -- metabolism
- Platelet Activation -- drug effects
- Platelet Glycoprotein GPIb-IX Complex -- metabolism
- Platelet Transfusion
- Radiation Chimera -- blood
- Thrombin -- pharmacology
- Thrombosis -- blood
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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