Sp1 is involved in Akt-mediated induction of VEGF expression through an HIF-1-independent mechanism. [electronic resource]
Producer: 20050408Description: 4841-53 p. digitalISSN:- 1059-1524
- Adenoviridae -- genetics
- Alkaline Phosphatase -- metabolism
- Base Sequence
- Binding Sites
- Blotting, Northern
- Blotting, Western
- Cell Line
- Cell Line, Tumor
- Collagen -- pharmacology
- DNA-Binding Proteins -- biosynthesis
- Densitometry
- Drug Combinations
- Genes, Reporter
- Green Fluorescent Proteins -- metabolism
- Humans
- Hypoxia
- Hypoxia-Inducible Factor 1
- Hypoxia-Inducible Factor 1, alpha Subunit
- Laminin -- pharmacology
- Molecular Sequence Data
- Neovascularization, Pathologic
- Nuclear Proteins -- biosynthesis
- Phosphates -- pharmacology
- Phosphatidylinositol 3-Kinases -- metabolism
- Phosphorylation
- Plasmids -- metabolism
- Plicamycin -- pharmacology
- Promoter Regions, Genetic
- Protein Binding
- Proteoglycans -- pharmacology
- RNA Interference
- RNA, Small Interfering -- metabolism
- Reverse Transcriptase Polymerase Chain Reaction
- Sp1 Transcription Factor -- physiology
- Transcription Factors -- biosynthesis
- Transcriptional Activation
- Transfection
- Up-Regulation
- Vascular Endothelial Growth Factor A -- biosynthesis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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