Investigation of the effect of the farnesyl protein transferase inhibitor R115777 on isoprenylation and intracellular signalling by the prostacyclin receptor. [electronic resource]
Producer: 20050422Description: 318-30 p. digitalISSN:- 0007-1188
- Alkyl and Aryl Transferases -- antagonists & inhibitors
- Animals
- Calcium -- metabolism
- Cell Line
- Cell Survival -- drug effects
- Cyclic AMP -- metabolism
- Dose-Response Relationship, Drug
- Drug Evaluation, Preclinical -- methods
- Enzyme Inhibitors -- pharmacology
- Humans
- Iloprost -- pharmacology
- Ireland
- Mice
- Molecular Chaperones -- drug effects
- Organophosphonates
- Protein Prenylation -- drug effects
- Quinolones -- chemistry
- Receptor Cross-Talk -- drug effects
- Receptors, Prostaglandin -- classification
- Time Factors
- Transfection -- methods
- Transferases -- antagonists & inhibitors
- Tritium
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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