Near completely humanized liver in mice shows human-type metabolic responses to drugs. [electronic resource]
Producer: 20040930Description: 901-12 p. digitalISSN:- 0002-9440
- Adolescent
- Adult
- Albumins -- metabolism
- Animals
- Child
- Chimera
- Complement C3-C5 Convertases -- antagonists & inhibitors
- Complement C3a -- metabolism
- Cytochrome P-450 Enzyme System -- genetics
- Enzyme Induction -- drug effects
- Enzyme Inhibitors -- pharmacology
- Hepatocytes -- cytology
- Heterozygote
- Homozygote
- Humans
- In Situ Hybridization
- Liver -- metabolism
- Liver Failure -- metabolism
- Male
- Methylcholanthrene -- pharmacology
- Mice
- Mice, SCID
- Mice, Transgenic
- Middle Aged
- RNA, Messenger -- analysis
- Rifampin -- pharmacology
- Transplantation, Heterologous
- Urokinase-Type Plasminogen Activator -- genetics
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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