Flavonoids inhibit tumor necrosis factor-alpha-induced up-regulation of intercellular adhesion molecule-1 (ICAM-1) in respiratory epithelial cells through activator protein-1 and nuclear factor-kappaB: structure-activity relationships. [electronic resource]
Producer: 20041103Description: 683-93 p. digitalISSN:- 0026-895X
- Apigenin
- Drug Interactions
- Epithelial Cells -- drug effects
- Flavonoids -- pharmacology
- Flavonols -- pharmacology
- Gene Expression Regulation -- drug effects
- Humans
- I-kappa B Kinase
- Intercellular Adhesion Molecule-1
- JNK Mitogen-Activated Protein Kinases
- Kaempferols -- pharmacology
- Luteolin
- Mitogen-Activated Protein Kinases -- genetics
- NF-kappa B -- metabolism
- Protein Kinases -- metabolism
- Protein Serine-Threonine Kinases -- metabolism
- Proto-Oncogene Proteins c-fos -- genetics
- RNA, Messenger -- drug effects
- Transcription Factor AP-1 -- physiology
- Tumor Cells, Cultured
- Tumor Necrosis Factor-alpha -- pharmacology
- U937 Cells
- Up-Regulation
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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