CpG island hypermethylation of the DNA repair enzyme methyltransferase predicts response to temozolomide in primary gliomas. [electronic resource]
Producer: 20050307Description: 4933-8 p. digitalISSN:- 1078-0432
- Adult
- Aged
- Alkylating Agents -- pharmacology
- Brain Neoplasms -- genetics
- Carmustine -- pharmacology
- CpG Islands
- DNA -- metabolism
- DNA Methylation
- DNA Repair
- Dacarbazine -- analogs & derivatives
- Female
- Glioma -- genetics
- Humans
- Male
- Middle Aged
- O(6)-Methylguanine-DNA Methyltransferase -- genetics
- Polymerase Chain Reaction
- Promoter Regions, Genetic
- Temozolomide
- Treatment Outcome
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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