Functional characterization of sonic hedgehog mutations associated with holoprosencephaly. [electronic resource]
Producer: 20041124Description: 42889-97 p. digitalISSN:- 0021-9258
- Actins -- chemistry
- Alkaline Phosphatase -- metabolism
- Amino Acid Sequence
- Animals
- Binding Sites
- Blotting, Western
- Cell Line
- Culture Media, Conditioned -- pharmacology
- Densitometry
- Drosophila
- Gene Deletion
- Genotype
- Hedgehog Proteins
- Holoprosencephaly -- genetics
- Humans
- Mice
- Mice, Inbred C3H
- Models, Genetic
- Models, Molecular
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Mutation
- Peptides -- chemistry
- Phenotype
- Protein Binding
- Protein Conformation
- Protein Structure, Tertiary
- Sequence Homology, Amino Acid
- Trans-Activators -- genetics
- Transfection
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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