An anti-Wnt-2 monoclonal antibody induces apoptosis in malignant melanoma cells and inhibits tumor growth. [electronic resource]
Producer: 20040909Description: 5385-9 p. digitalISSN:- 0008-5472
- Adaptor Proteins, Signal Transducing
- Animals
- Antibodies, Monoclonal -- therapeutic use
- Apoptosis -- immunology
- Cytoskeletal Proteins -- metabolism
- Dishevelled Proteins
- Down-Regulation
- Humans
- Inhibitor of Apoptosis Proteins
- Ligands
- Melanoma -- immunology
- Mice
- Mice, Nude
- Microtubule-Associated Proteins -- antagonists & inhibitors
- Neoplasm Proteins
- Phosphoproteins -- metabolism
- Proto-Oncogene Proteins -- antagonists & inhibitors
- RNA, Small Interfering -- pharmacology
- Skin Neoplasms -- immunology
- Survivin
- Trans-Activators -- metabolism
- Wnt2 Protein
- Women
- beta Catenin
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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