Rereplication by depletion of geminin is seen regardless of p53 status and activates a G2/M checkpoint. [electronic resource]
Producer: 20040909Description: 7140-50 p. digitalISSN:- 0270-7306
- Apoptosis -- physiology
- CDC2 Protein Kinase -- metabolism
- Caffeine -- metabolism
- Cell Cycle -- physiology
- Cell Cycle Proteins -- genetics
- Cell Line, Tumor
- Checkpoint Kinase 1
- Checkpoint Kinase 2
- Cyclin B -- metabolism
- DNA Replication
- Enzyme Activation
- Geminin
- Genes, cdc
- Genomic Instability
- Histones -- metabolism
- Humans
- Protein Kinases -- genetics
- Protein Serine-Threonine Kinases -- genetics
- RNA Interference
- RNA, Small Interfering -- genetics
- Tumor Suppressor Protein p53 -- genetics
- cdc25 Phosphatases -- metabolism
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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