Lepirudin prevents lethal effects of Shiga toxin in a canine model. [electronic resource]
Producer: 20050215Description: 387-93 p. digitalISSN:- 0340-6245
- Animals
- Anticoagulants -- toxicity
- Blood Platelets -- metabolism
- Cell-Free System
- Coagulants -- pharmacology
- Dogs
- Fibrinogen -- biosynthesis
- Hemolytic-Uremic Syndrome -- drug therapy
- Hirudins -- analogs & derivatives
- Kidney Glomerulus -- pathology
- Microscopy, Electron, Transmission
- Partial Thromboplastin Time
- Prothrombin -- genetics
- Prothrombin Time
- Recombinant Proteins -- metabolism
- Shiga Toxin 1 -- toxicity
- Shiga Toxin 2 -- toxicity
- Thrombin -- metabolism
- Time Factors
- von Willebrand Factor -- genetics
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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