Celiprolol, a vasodilatory beta-blocker, inhibits pressure overload-induced cardiac hypertrophy and prevents the transition to heart failure via nitric oxide-dependent mechanisms in mice. [electronic resource]
Producer: 20050208Description: 692-9 p. digitalISSN:- 1524-4539
- Adrenergic beta-1 Receptor Antagonists
- Adrenergic beta-Antagonists -- pharmacology
- Animals
- Cardiomegaly -- etiology
- Celiprolol -- pharmacology
- Cells, Cultured -- drug effects
- Disease Progression
- Drug Evaluation, Preclinical
- Enzyme Induction -- drug effects
- Fibrosis
- Gene Expression Regulation -- drug effects
- Heart Failure -- etiology
- Hypertrophy
- Isoproterenol -- pharmacology
- Male
- Mice
- Mice, Inbred C57BL
- Myocardium -- pathology
- Myocytes, Cardiac -- drug effects
- NG-Nitroarginine Methyl Ester -- pharmacology
- Natriuretic Peptide, Brain -- biosynthesis
- Nitric Oxide -- physiology
- Nitric Oxide Synthase -- genetics
- Nitric Oxide Synthase Type II
- Nitric Oxide Synthase Type III
- Phenylephrine -- pharmacology
- Pressure -- adverse effects
- RNA, Messenger -- biosynthesis
- Rats
- Transcription, Genetic -- drug effects
- Vasodilator Agents -- pharmacology
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.