A specific antagonist of the p110delta catalytic component of phosphatidylinositol 3'-kinase, IC486068, enhances radiation-induced tumor vascular destruction. [electronic resource]
Producer: 20040909Description: 4893-9 p. digitalISSN:- 0008-5472
- Animals
- Catalytic Domain
- Cell Movement -- drug effects
- Cell Survival -- drug effects
- Cells, Cultured
- Endothelium, Vascular -- cytology
- Enzyme Inhibitors -- pharmacology
- Humans
- Mice
- Neoplasms, Experimental -- blood supply
- Neovascularization, Pathologic -- drug therapy
- Phosphoinositide-3 Kinase Inhibitors
- Quinazolines -- pharmacology
- Radiation-Sensitizing Agents -- pharmacology
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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