The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins. [electronic resource]
Producer: 20040920Description: 213-23 p. digitalISSN:- 0021-9525
- Animals
- Cell Survival
- Chemotaxis
- Fibroblasts -- cytology
- Insulin -- metabolism
- Insulin Receptor Substrate Proteins
- Insulin-Like Growth Factor I -- physiology
- Intracellular Signaling Peptides and Proteins
- Mice
- Phosphatidylinositol 3-Kinases -- metabolism
- Phosphoproteins -- antagonists & inhibitors
- Phosphorylation
- Proteins -- physiology
- Repressor Proteins -- physiology
- Ribosomal Protein S6 Kinases -- antagonists & inhibitors
- Signal Transduction
- Tuberous Sclerosis Complex 1 Protein
- Tuberous Sclerosis Complex 2 Protein
- Tumor Suppressor Proteins -- physiology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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