Inhibition of fatty acid synthase (FAS) suppresses HER2/neu (erbB-2) oncogene overexpression in cancer cells. [electronic resource]
Producer: 20040826Description: 10715-20 p. digitalISSN:- 0027-8424
- 4-Butyrolactone -- analogs & derivatives
- Antibodies, Monoclonal -- metabolism
- Antibodies, Monoclonal, Humanized
- Antifungal Agents -- metabolism
- Antineoplastic Agents -- metabolism
- Apoptosis
- Biomarkers, Tumor
- Breast Neoplasms -- genetics
- Cell Line
- Cell Size
- Cell Survival
- Cerulenin -- metabolism
- Fatty Acid Synthases -- antagonists & inhibitors
- Female
- Gene Expression Regulation, Neoplastic
- Genes, erbB-2
- Humans
- Ovarian Neoplasms -- genetics
- RNA, Small Interfering -- genetics
- Receptor, ErbB-2 -- genetics
- Signal Transduction
- Transcription Factors -- genetics
- Trastuzumab
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Publication Type: Journal Article
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