Mitochondrial Na+ overload is caused by oxidative stress and leads to activation of the caspase 3- dependent apoptotic machinery. [electronic resource]
Producer: 20050405Description: 1442-4 p. digitalISSN:- 1530-6860
- Apoptosis -- drug effects
- Calcium -- metabolism
- Caspase 3
- Caspases -- metabolism
- Cytochromes c -- metabolism
- Cytosol -- drug effects
- Enzyme Activation -- drug effects
- Hydrogen Peroxide -- metabolism
- Mitochondria -- drug effects
- Myocytes, Cardiac -- cytology
- Oxidative Stress -- drug effects
- Signal Transduction -- drug effects
- Sodium -- metabolism
- Sodium-Calcium Exchanger -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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