Bcl-2 phosphorylation and apoptosis activated by damaged microtubules require mTOR and are regulated by Akt. [electronic resource]
Producer: 20040902Description: 5781-91 p. digitalISSN:- 0950-9232
- Apoptosis -- drug effects
- Cells, Cultured
- Dose-Response Relationship, Drug
- G2 Phase -- drug effects
- Microtubules -- drug effects
- Mitosis -- drug effects
- Mutation
- Nocodazole -- pharmacology
- Paclitaxel -- pharmacology
- Phosphorylation
- Protein Kinases -- metabolism
- Protein Serine-Threonine Kinases -- genetics
- Proto-Oncogene Proteins -- genetics
- Proto-Oncogene Proteins c-akt
- Proto-Oncogene Proteins c-bcl-2 -- drug effects
- Ribosomal Protein S6 Kinases, 70-kDa -- metabolism
- Serine -- metabolism
- Signal Transduction
- Sirolimus -- pharmacology
- TOR Serine-Threonine Kinases
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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