The immune modulator FTY720 targets sphingosine-kinase-dependent migration of human monocytes in response to amyloid beta-protein and its precursor. [electronic resource]
Producer: 20050208Description: 1309-11 p. digitalISSN:- 1530-6860
- 1-Methyl-3-isobutylxanthine -- pharmacology
- Amyloid beta-Peptides -- pharmacology
- Amyloid beta-Protein Precursor -- pharmacology
- Androstadienes -- pharmacology
- Bombesin -- pharmacology
- Calcitonin Gene-Related Peptide -- pharmacology
- Cell Movement -- drug effects
- Chemotaxis, Leukocyte -- drug effects
- Cholera Toxin -- pharmacology
- Drug Evaluation, Preclinical
- Enzyme Inhibitors -- pharmacology
- Fingolimod Hydrochloride
- Gene Expression Regulation -- drug effects
- Heterotrimeric GTP-Binding Proteins -- physiology
- Humans
- Immunologic Factors -- pharmacology
- Indoles -- pharmacology
- Leukocytes, Mononuclear -- cytology
- Maleimides -- pharmacology
- N-Formylmethionine Leucyl-Phenylalanine -- pharmacology
- Neuropeptides -- pharmacology
- Pertussis Toxin -- pharmacology
- Phosphoinositide-3 Kinase Inhibitors
- Phosphorylation -- drug effects
- Phosphotransferases (Alcohol Group Acceptor) -- antagonists & inhibitors
- Propylene Glycols -- pharmacology
- Protein Kinase Inhibitors -- pharmacology
- Protein Processing, Post-Translational -- drug effects
- RNA, Messenger -- biosynthesis
- Receptors, Lysosphingolipid -- agonists
- Secretogranin II
- Sphingosine -- analogs & derivatives
- Staurosporine -- pharmacology
- Tyrphostins -- pharmacology
- Vasoactive Intestinal Peptide -- pharmacology
- Wortmannin
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Publication Type: Comparative Study; Journal Article
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